| http://purl.uniprot.org/citations/10691732 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10691732 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10691732 | http://www.w3.org/2000/01/rdf-schema#comment | "Although a small decrease in survival and increase in tumor incidence was observed in ATR(+/-) mice, ATR(-/-) embryos die early in development, subsequent to the blastocyst stage and prior to 7.5 days p.c. In culture, ATR(-/-) blastocysts cells continue to cycle into mitosis for 2 days but subsequently fail to expand and die of caspase-dependent apoptosis. Importantly, caspase-independent chromosome breaks are observed in ATR(-/-) cells prior to widespread apoptosis, implying that apoptosis is caused by a loss of genomic integrity. These data show that ATR is essential for early embryonic development and must function in processes other than regulation of p53."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/author | "Baltimore D."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/author | "Baltimore D."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/author | "Brown E.J."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/author | "Brown E.J."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/pages | "397-402"xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/pages | "397-402"xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/title | "ATR disruption leads to chromosomal fragmentation and early embryonic lethality."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/title | "ATR disruption leads to chromosomal fragmentation and early embryonic lethality."xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/10691732 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10691732 |
| http://purl.uniprot.org/citations/10691732 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10691732 |
| http://purl.uniprot.org/citations/10691732 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10691732 |
| http://purl.uniprot.org/citations/10691732 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10691732 |
| http://purl.uniprot.org/uniprot/Q9JKK8 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10691732 |
| http://purl.uniprot.org/uniprot/Q9JKK8#attribution-8C957B9714A7F1B251667238D7B0AD92 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10691732 |
| http://purl.uniprot.org/uniprot/Q9JKK8#attribution-F42DDD9C268DF2E1C6493665E0FB1E91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10691732 |
| http://purl.uniprot.org/uniprot/#_Q9JKK8-citation-10691732 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10691732 |