| http://purl.uniprot.org/citations/10693762 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10693762 | http://www.w3.org/2000/01/rdf-schema#comment | "In order to study the role of calcium/calmodulin kinase II (CaMKII) in T cells, we generated transgenic mice expressing CaMKIIgammaB* (T287D), a partially calcium-independent mutant of CaMKIIgammaB. In these mice, the size of the thymus was increased 1.5-to 2-fold, at least in part due to an increase in the lifespan of double-positive (DP) thymocytes. More importantly, there was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype. These T cells were bonafide memory cells as assessed by a variety of criteria. In addition, T cells from wild-type mice acquired calcium-independent CaMKII activity after several rounds of antigen-stimulated division. We propose that CaMKII controls a distinct process of activation-induced cellular differentiation."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80681-9"xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/author | "Kane L.P."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/author | "Hedrick S.M."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/author | "Gardner P."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/author | "Bui J.D."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/author | "Calbo S."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/author | "Hayden-Martinez K."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/pages | "457-467"xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/title | "A role for CaMKII in T cell memory."xsd:string |
| http://purl.uniprot.org/citations/10693762 | http://purl.uniprot.org/core/volume | "100"xsd:string |
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