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http://purl.uniprot.org/citations/10710421http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10710421http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10710421http://www.w3.org/2000/01/rdf-schema#comment"The Spo11 protein of yeast has been found to be covalently bound to double-strand breaks in meiosis, demonstrating a unique role of the protein in the formation of these breaks. Homologues of the SPO11 gene have been found in various eukaryotes, indicating that the machinery involved in meiotic recombination is conserved in eukaryotes. Here we report on SPO11 homologues in plants. In contrast to what is known from other eukaryotes, Arabidopsis thaliana carries in its genome at least two SPO11 homologues, AtSPO11-1 and AtSPO11-2. Both genes are not more closely related to each other than to other eukaryotic SPO11 homologues, indicating that they did not arise via a recent duplication event during higher plant evolution. For both genes three different poly-adenylation sites were found. AtSPO11-1 is expressed not only in generative but also to a lesser extent in somatic tissues. We were able to detect in different organs various AtSPO11-1 cDNAs in which introns were differently spliced-a surprising phenomenon also reported for SPO11 homologues in mammals. In the case of AtSPO11-2 we found that the 3' end of the mRNA is overlapping with a mRNA produced by a gene located in inverse orientation next to it. This points to a possible antisense regulation mechanism. Our findings hint to the intriguing possibility that, at least for plants, Spo11-like proteins might have more and possibly other biological functions than originally anticipated for yeast."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.org/dc/terms/identifier"doi:10.1093/nar/28.7.1548"xsd:string
http://purl.uniprot.org/citations/10710421http://purl.org/dc/terms/identifier"doi:10.1093/nar/28.7.1548"xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/author"Puchta H."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/author"Puchta H."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/author"Hartung F."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/author"Hartung F."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/pages"1548-1554"xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/pages"1548-1554"xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/title"Molecular characterisation of two paralogous SPO11 homologues in Arabidopsis thaliana."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/title"Molecular characterisation of two paralogous SPO11 homologues in Arabidopsis thaliana."xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/volume"28"xsd:string
http://purl.uniprot.org/citations/10710421http://purl.uniprot.org/core/volume"28"xsd:string
http://purl.uniprot.org/citations/10710421http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10710421
http://purl.uniprot.org/citations/10710421http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10710421
http://purl.uniprot.org/citations/10710421http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10710421
http://purl.uniprot.org/citations/10710421http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10710421
http://purl.uniprot.org/uniprot/Q9M4A1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10710421
http://purl.uniprot.org/uniprot/Q9M4A2http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10710421