| http://purl.uniprot.org/citations/10713668 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10713668 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10713668 | http://www.w3.org/2000/01/rdf-schema#comment | "We have previously shown that the transcription factor AP-1 regulates the expression of genes which allow neoplastically transformed rat fibroblasts to become invasive. Searches for further AP-1 target genes led to the identification of a gene encoding a novel rat kelch family member, named kelch related protein 1 (Krp1). Kelch family members are characterized by a series of repeats at their carboxyl terminus and a BTB/POZ domain near their amino terminus. Rat Krp1 has a primarily cytoplasmic localization, and a small fraction appears to accumulate and co-localize with F-actin at membrane ruffle-like structures in the tips of pseudopodia. Overexpression of Krp1 in transformed rat fibroblasts led to the formation of dramatically elongated pseudopodia, while expression of truncated Krp1 polypeptides resulted in a reduction in the length of pseudopodia. We propose that the transformation-specific expression of Krp1 is required for pseudopod elongation, which are structures that are required for cell motility and invasion."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1203433"xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1203433"xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Spence H.J."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Spence H.J."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Ozanne B.W."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Ozanne B.W."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Buchanan S.J."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Buchanan S.J."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Ewart K."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Ewart K."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Fitzgerald U."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Fitzgerald U."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Johnston I.P."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/author | "Johnston I.P."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/pages | "1266-1276"xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/pages | "1266-1276"xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/title | "Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells."xsd:string |
| http://purl.uniprot.org/citations/10713668 | http://purl.uniprot.org/core/title | "Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells."xsd:string |