http://purl.uniprot.org/citations/10733525 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10733525 | http://www.w3.org/2000/01/rdf-schema#comment | "Female reproductive hormones control mammary gland morphogenesis. In the absence of the progesterone receptor (PR) from the mammary epithelium, ductal side-branching fails to occur. We can overcome this defect by ectopic expression of the protooncogene Wnt-1. Transplantation of mammary epithelia from Wnt-4(-)/(-) mice shows that Wnt-4 has an essential role in side-branching early in pregnancy. PR and Wnt-4 mRNAs colocalize to the luminal compartment of the ductal epithelium. Progesterone induces Wnt-4 in mammary epithelial cells and is required for increased Wnt-4 expression during pregnancy. Thus, Wnt signaling is essential in mediating progesterone function during mammary gland morphogenesis."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Tan J."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Dey S.K."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Weinberg R.A."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "McMahon A.P."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "McMahon J.A."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Elenbaas B."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Brisken C."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Chavarria T."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/author | "Heineman A."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/pages | "650-654"xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/title | "Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling."xsd:string |
http://purl.uniprot.org/citations/10733525 | http://purl.uniprot.org/core/volume | "14"xsd:string |
http://purl.uniprot.org/citations/10733525 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10733525 |
http://purl.uniprot.org/citations/10733525 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10733525 |
http://purl.uniprot.org/uniprot/Q00175#attribution-D49D2F67A524D8BFA7294EAE008D5D4D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10733525 |
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http://purl.uniprot.org/uniprot/#_Q3UQA6-mappedCitation-10733525 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10733525 |