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http://purl.uniprot.org/citations/10734216http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10734216http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10734216http://www.w3.org/2000/01/rdf-schema#comment"Certain exogenously-supplied sterols, like ergost-8-enol, are efficiently converted into ergosterol in yeast. We have taken advantage of this property to study the regulation of the Delta8-Delta7-sterol isomerase-encoding ERG2 gene in an ergosterol auxotrophic mutant devoid of squalene-synthase activity. Ergosterol starvation leads to an 8-16-fold increase in ERG2 gene expression. Such an increase was also observed in wild-type cells either grown anaerobically or treated with SR31747A a sterol isomerase inhibitor. Exogenously-supplied zymosterol is entirely transformed into ergosterol, which represses ERG2 transcription. By contrast, exogenously-supplied ergosterol has little or no effect on ERG2 transcription."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(00)01300-4"xsd:string
http://purl.uniprot.org/citations/10734216http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(00)01300-4"xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Loison G."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Loison G."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Karst F."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Karst F."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Silve S."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Silve S."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Dupuy P.H."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Dupuy P.H."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Soustre I."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/author"Soustre I."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/pages"102-106"xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/pages"102-106"xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/title"Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/title"Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/volume"470"xsd:string
http://purl.uniprot.org/citations/10734216http://purl.uniprot.org/core/volume"470"xsd:string