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http://purl.uniprot.org/citations/10749171http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10749171http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10749171http://www.w3.org/2000/01/rdf-schema#comment"Dynamin-like protein, a large GTP-binding protein, has recently been cloned, and studies have suggested that it is involved in the formation of coated vesicles. In this report, the differential expression of four human dynamin-like protein splice variants (HdynIV-wildtype [WT], -11, -26, and -37) from various brain tumors was identified by reverse transcription/polymerase chain reaction (RT-PCR). One novel variant (HdynIV-11), not described previously, was identified. The four alternatively spliced variants exhibited tissue specificity in normal tissues. The HdynIV-WT was strongly expressed in the brain, whereas HdynIV-37 was expressed in all tissues examined. Moreover, HdynIV-26 was dominant in the liver and apparently overexpressed in all astrocytomas and most meningiomas and adenomas. This report suggests that HdynIV-26 may cause aberrant protein trafficking and alter vesicle formation in brain tumors. Our results also suggest that dynamin-like protein is associated with various brain tumors and, more importantly, that aberrant expression of the HdynIV-26 variant may play a role in brain tumorigenesis."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.org/dc/terms/identifier"doi:10.1089/104454900314573"xsd:string
http://purl.uniprot.org/citations/10749171http://purl.org/dc/terms/identifier"doi:10.1089/104454900314573"xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Hong Y.-R."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Hong Y.-R."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Chen C.-H."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Chen C.-H."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Chou C.-K."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Chou C.-K."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Howng S.-L."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Howng S.-L."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Hwang S.-L."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Hwang S.-L."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Liao C.-H."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/author"Liao C.-H."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/name"DNA Cell Biol."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/name"DNA Cell Biol."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/pages"189-194"xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/pages"189-194"xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/title"Differential expression of four human dynamin-like protein variants in brain tumors."xsd:string
http://purl.uniprot.org/citations/10749171http://purl.uniprot.org/core/title"Differential expression of four human dynamin-like protein variants in brain tumors."xsd:string