| http://purl.uniprot.org/citations/10753924 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10753924 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10753924 | http://www.w3.org/2000/01/rdf-schema#comment | "Elongin is a transcription elongation factor that was first identified in mammalian systems and is composed of the three subunits, elongin A, B, and C. Sequence homologues of elongin A and elongin C, but not elongin B, were identified in the yeast genome. Neither yeast elongin A nor C sequence homologues was required for cell viability. The two gene products could be purified from yeast as a complex. A recombinant form of the complex, which could only be produced in bacteria if the gene products were co-expressed, was purified over several chromatographic steps. The complex did not stimulate transcription elongation by yeast RNA polymerase II. Using limited proteolysis, the N-terminal 144 residues of yeast elongin A were shown to be sufficient for interaction with yeast elongin C. The purified complex of yeast elongin C/elongin A(1-143) was analyzed using circular dichroism and nuclear magnetic spectroscopy. These studies revealed that yeast elongin A is unfolded but undergoes a dramatic modification of its structure in the presence of elongin C, and that elongin C forms a stable dimer in the absence of elongin A."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.275.15.11174"xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.275.15.11174"xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Arrowsmith C.H."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Arrowsmith C.H."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Edwards A.M."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Edwards A.M."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Koth C.M."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Koth C.M."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Botuyan M.V."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Botuyan M.V."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Friesen J.D."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Friesen J.D."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Conaway J.W."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Conaway J.W."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Conaway R.C."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Conaway R.C."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Chazin W.J."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Chazin W.J."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Jansma D.B."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Jansma D.B."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Moreland R.J."xsd:string |
| http://purl.uniprot.org/citations/10753924 | http://purl.uniprot.org/core/author | "Moreland R.J."xsd:string |