| http://purl.uniprot.org/citations/10760573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10760573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10760573 | http://www.w3.org/2000/01/rdf-schema#comment | "A novel murine cysteine protease from the family of papain-like cysteine proteinases was identified by dbEST-database search. A 1. 4-kb full-length cDNA encoding a predicted polypeptide of 306 amino acids was characterized. The new protease, tentatively named cathepsin Z, exhibits all features characteristics of a papain-like cysteine protease, including the highly conserved residues of the 'catalytic triad'. Cathepsin Z shares only 26-35% overall homology with previously described mammalian papain-like cysteine peptidases and has an unusually short propeptide, which may indicate that it is a member of a putative new subfamily within the family of papain-like cysteine peptidases. Genomic clones covering the murine and human cathepsin Z genes were isolated. They comprise six exons and five introns spanning a 12-kb region of genomic DNA, respectively. Murine cathepsin Z was mapped to chromosome 2, a region with synteny homology to a region of human chromosome 20 to which human cathepsin Z has been mapped previously. Northern blot analysis revealed ubiquitous expression of murine cathepsin Z. Multiple transcriptional start sites were identified for the murine cathepsin Z gene and together with the absence of a TATA box, a high G+C content, a CpG island and the presence of several Sp1-binding sites in the promoter region, murine cathepsin Z may be classified as a 'housekeeping' gene."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0167-4781(00)00021-x"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0167-4781(00)00021-x"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/author | "Peters C."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/author | "Peters C."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/author | "Deussing J."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/author | "Deussing J."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/author | "von Olshausen I."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/author | "von Olshausen I."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/name | "Biochim. Biophys. Acta"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/name | "Biochim. Biophys. Acta"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/pages | "93-106"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/pages | "93-106"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/title | "Murine and human cathepsin Z: cDNA-cloning, characterization of the genes and chromosomal localization."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/title | "Murine and human cathepsin Z: cDNA-cloning, characterization of the genes and chromosomal localization."xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/volume | "1491"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://purl.uniprot.org/core/volume | "1491"xsd:string |
| http://purl.uniprot.org/citations/10760573 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10760573 |
| http://purl.uniprot.org/citations/10760573 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10760573 |
| http://purl.uniprot.org/citations/10760573 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10760573 |
| http://purl.uniprot.org/citations/10760573 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10760573 |