| http://purl.uniprot.org/citations/10767298 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10767298 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10767298 | http://www.w3.org/2000/01/rdf-schema#comment | "14-3-3 sigma, implicated in cell cycle arrest by p53, was cloned by expression cloning through cyclin-dependent kinase 2 (CDK2) association. 14-3-3 sigma shares cyclin-CDK2 binding motifs with different cell cycle regulators, including p107, p130, p21(CIP1), p27(KIP1), and p57(KIP2), and is associated with cyclin.CDK complexes in vitro and in vivo. Overexpression of 14-3-3 sigma obstructs cell cycle entry by inhibiting cyclin-CDK activity in many breast cancer cell lines. Overexpression of 14-3-3 sigma can also inhibit cell proliferation and prevent anchorage-independent growth of these cell lines. These findings define 14-3-3 sigma as a negative regulator of the cell cycle progression and suggest that it has an important function in preventing breast tumor cell growth."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.M905616199"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m905616199"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Lee M.H."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Lee M.H."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Yang H.Y."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Yang H.Y."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Neal C."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Neal C."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Laronga C."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/author | "Laronga C."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/pages | "23106-23112"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/pages | "23106-23112"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/title | "Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/title | "Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression."xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/volume | "275"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://purl.uniprot.org/core/volume | "275"xsd:string |
| http://purl.uniprot.org/citations/10767298 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10767298 |
| http://purl.uniprot.org/citations/10767298 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10767298 |