| http://purl.uniprot.org/citations/10772929 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10772929 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10772929 | http://www.w3.org/2000/01/rdf-schema#comment | "Midkine (MK) is a heparin-binding growth factor with migration-promoting and survival-promoting activities. To identify signaling receptor(s) of MK, membrane glycoproteins with MK-binding activity were isolated from day 13 mouse embryos by lectin- and MK-affinity chromatography. SDS-PAGE followed by protein sequence analysis revealed the presence of LDL receptor-related protein (LRP) and NCAM in the fraction. The dissociation constant of binding between LRP and MK was 3.5 nM. Receptor-associated protein (RAP), which interfered with the binding, inhibited MK-dependent survival of embryonic neurons. Brushin/megalin, which is also a high molecular weight protein belonging to the LDL receptor family, bound to MK less strongly than LRP. These findings suggest that LRP is a component of the receptor complex for MK."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.2549"xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.2549"xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Sakaguchi N."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Sakaguchi N."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Muramatsu T."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Muramatsu T."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Sakuma S."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Sakuma S."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Zou K."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Zou K."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Muramatsu H."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Muramatsu H."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Ikematsu S."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/author | "Ikematsu S."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/pages | "936-941"xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/pages | "936-941"xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/title | "LDL receptor-related protein as a component of the midkine receptor."xsd:string |
| http://purl.uniprot.org/citations/10772929 | http://purl.uniprot.org/core/title | "LDL receptor-related protein as a component of the midkine receptor."xsd:string |