| http://purl.uniprot.org/citations/10778858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10778858 | http://www.w3.org/2000/01/rdf-schema#comment | "We present evidence that Rb forms a repressor containing histone deacetylase (HDAC) and the hSWI/SNF nucleosome remodeling complex, which inhibits transcription of genes for cyclins E and A and arrests cells in the G1 phase of the cell cycle. Phosphorylation of Rb by cyclin D/cdk4 disrupts association with HDAC, relieving repression of the cyclin E gene and G1 arrest. However, the Rb-hSWI/SNF complex persists and is sufficient to maintain repression of the cyclin A and cdc2 genes, inhibiting exit from S phase. HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF then appear to maintain the order of cyclin E and A expression during the cell cycle, which in turn regulates exit from G1 and from S phase, respectively."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80625-x"xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Ma D."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Zhang H.S."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Dean D.C."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Harbour J.W."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Luo R.X."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Postigo A.A."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Gavin M."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/author | "Dahiya A."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/pages | "79-89"xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/title | "Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF."xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://purl.uniprot.org/core/volume | "101"xsd:string |
| http://purl.uniprot.org/citations/10778858 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10778858 |
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| http://purl.uniprot.org/uniprot/P60709#attribution-3F8774AAD740FDBD1B85664FDC9265BA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10778858 |
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