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http://purl.uniprot.org/citations/10791828http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10791828http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10791828http://www.w3.org/2000/01/rdf-schema#comment"Sex-lethal (Sxl) is Drosophila melanogaster's key regulating gene in the sex-determining cascade. Its homologue in Megaselia scalaris, the chromosome 3 gene Megsxl, codes for a protein with an overall similarity of 77% with the corresponding D. melanogaster sequence. Expression in M. scalaris, however, is very unlike that in D. melanogaster. Megsxl transcripts with a long ORF occur in both sexes. Differential splicing is conserved but not sex-specific. There are several splice variants, among them one is common to gonads and somatic tissues of all developmental stages investigated, one is specific for ovaries and embryos, and a third one is not found in ovaries. In the ovary, Megsxl is heavily transcribed in nurse cells and transported into eggs. These results suggest a non-sex-determining function during early embryogenesis; the presence of Megsxl RNA in testes and somatic tissues calls for other (or more) functions."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.org/dc/terms/identifier"doi:10.1139/g99-132"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.org/dc/terms/identifier"doi:10.1139/g99-132"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Sievert V."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Sievert V."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Paululat A."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Paululat A."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Traut W."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Traut W."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Kuhn S."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/author"Kuhn S."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/name"Genome"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/name"Genome"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/pages"382-390"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/pages"382-390"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/title"Sequence conservation and expression of the sex-lethal homologue in the fly Megaselia scalaris."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/title"Sequence conservation and expression of the sex-lethal homologue in the fly Megaselia scalaris."xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/volume"43"xsd:string
http://purl.uniprot.org/citations/10791828http://purl.uniprot.org/core/volume"43"xsd:string
http://purl.uniprot.org/citations/10791828http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10791828
http://purl.uniprot.org/citations/10791828http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10791828