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http://purl.uniprot.org/citations/10791955http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10791955http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10791955http://www.w3.org/2000/01/rdf-schema#comment"In this study, we report the identification of a novel tumor necrosis factor receptor-associated factor 3 (TRAF3)-interacting protein designated MIP-T3. MIP-T3 is a 83-kDa protein with no significant homology to known mammalian proteins. MIP-T3 mRNA and TRAF3 mRNA are ubiquitously expressed, and TRAF3 is the only TRAF protein to interact with MIP-T3. The MIP-T3-TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3. To our knowledge, this is the first case of a TRAF-binding protein that interacts with a single member of the TRAF family specifically through a TRAF-N coiled-coil domain. MIP-T3 binds to Taxol-stabilized microtubules and to tubulin in vitro, and MIP-T3 recruits TRAF3 to microtubules when both proteins are overexpressed in HeLa cells. In a 293 cell line stably expressing CD40, TRAF3 is released from the TRAF3.MIP-T3 complex and recruited to the CD40 receptor upon CD40 ligand stimulation. MIP-T3 may provide a novel mechanism in sequestering TRAF3 to the cytoskeletal network."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m001095200"xsd:string
http://purl.uniprot.org/citations/10791955http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m001095200"xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/author"Ling L."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/author"Ling L."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/author"Goeddel D.V."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/author"Goeddel D.V."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/pages"23852-23860"xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/pages"23852-23860"xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/title"MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/title"MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network."xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/volume"275"xsd:string
http://purl.uniprot.org/citations/10791955http://purl.uniprot.org/core/volume"275"xsd:string
http://purl.uniprot.org/citations/10791955http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10791955
http://purl.uniprot.org/citations/10791955http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10791955
http://purl.uniprot.org/citations/10791955http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10791955
http://purl.uniprot.org/citations/10791955http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10791955
http://purl.uniprot.org/uniprot/P78552http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10791955
http://purl.uniprot.org/uniprot/Q13114http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10791955