http://purl.uniprot.org/citations/10794172 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10794172 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10794172 | http://www.w3.org/2000/01/rdf-schema#comment | "In the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe replication factor C (RF-C) plays key roles both in chromosomal DNA replication and in DNA replication checkpoint function. At the replication fork, the five-subunit RF-C complex functions to load the trimeric polymerase accessory factor PCNA onto DNA. PCNA then acts as a sliding clamp, tethering Pol delta to the DNA to maximise its processivity. Here we describe the cloning of the S. pombe rfc3+ gene, encoding a homologue of the S. cerevisiae Rfc3 and human hRFC36 proteins. The 1026 bp rfc3+ ORF is interrupted by five introns, ranging in size from 49 to 165 bp. The spliced ORF is predicted to encode a 342 amino-acid protein that is approximately 50% identical at the amino acid sequence level to the S. cerevisiae Rfc3 and human hRFC36 proteins. As expected, S. pombe rfc3+ is an essential gene, with rfc3delta cells being defective for DNA replication. Loss of rfc3+ function can be rescued by heterologous expression of either the S. cerevisiae Rfc3 or human hRFC36 proteins in S. pombe."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.org/dc/terms/identifier | "doi:10.1007/s002940050514"xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.org/dc/terms/identifier | "doi:10.1007/s002940050514"xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/author | "Gray F.C."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/author | "Gray F.C."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/author | "MacNeill S.A."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/author | "MacNeill S.A."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/name | "Curr. Genet."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/name | "Curr. Genet."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/pages | "159-167"xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/pages | "159-167"xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/title | "The Schizosaccharomyces pombe rfc3+ gene encodes a homologue of the human hRFC36 and Saccharomyces cerevisiae Rfc3 subunits of replication factor C."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/title | "The Schizosaccharomyces pombe rfc3+ gene encodes a homologue of the human hRFC36 and Saccharomyces cerevisiae Rfc3 subunits of replication factor C."xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/volume | "37"xsd:string |
http://purl.uniprot.org/citations/10794172 | http://purl.uniprot.org/core/volume | "37"xsd:string |
http://purl.uniprot.org/citations/10794172 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10794172 |
http://purl.uniprot.org/citations/10794172 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10794172 |
http://purl.uniprot.org/citations/10794172 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10794172 |
http://purl.uniprot.org/citations/10794172 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10794172 |
http://purl.uniprot.org/uniprot/O14003 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10794172 |
http://purl.uniprot.org/uniprot/#_O14003-citation-10794172 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10794172 |