| http://purl.uniprot.org/citations/10801972 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10801972 | http://www.w3.org/2000/01/rdf-schema#comment | "Two new high-resolution cocrystal structures of EcoRV endonuclease bound to DNA show that a large variation in DNA-bending angles is sampled in the ground state binary complex. Together with previous structures, these data reveal a contiguous series of protein conformational states delineating a specific trajectory for the induced-fit pathway. Rotation of the DNA-binding domains, together with movements of two symmetry-related helices binding in the minor groove, causes base unstacking at a key base-pair step and propagates structural changes that assemble the active sites. These structures suggest a complex mechanism for DNA bending that depends on forces generated by interacting protein segments, and on selective neutralization of phosphate charges along the inner face of the bent double helix."xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.090370797"xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/author | "Perona J.J."xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/author | "Horton N.C."xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/pages | "5729-5734"xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/title | "Crystallographic snapshots along a protein-induced DNA-bending pathway."xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://purl.uniprot.org/core/volume | "97"xsd:string |
| http://purl.uniprot.org/citations/10801972 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10801972 |
| http://purl.uniprot.org/citations/10801972 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10801972 |
| http://purl.uniprot.org/uniprot/#_P04390-mappedCitation-10801972 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10801972 |
| http://purl.uniprot.org/uniprot/P04390 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10801972 |