http://purl.uniprot.org/citations/10818169 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10818169 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10818169 | http://www.w3.org/2000/01/rdf-schema#comment | "The studies reported here were designed to investigate the role of the mutation eat-4 in the response to tap and in habituation in the nematode Caenorhabditis elegans. In C. elegans eat-4 has been found to affect a number of glutamatergic pathways. It has been hypothesized to positively regulate glutaminase activity and therefore glutamatergic neurotransmission. In the eat-4(ky5) loss-of-function worms, there is presumably insufficient glutamate available for sustained transmission. In the experiments reported here eat-4 worms showed no differences from wild-type in the magnitude of response to a single tap, indicating that the neural circuit underlying the response was intact and functional in the mutant worms. However, when eat-4 worms were given repeated taps the resulting habituation was different from that seen in wild-type worms: eat-4 worms habituate more rapidly and recover more slowly than wild-type worms at all interstimulus intervals tested. In addition, eat-4 worms do not show dishabituation. The same transgene rescues pharyngeal activity defects and both the habituation and dishabituation deficits seen in the eat-4 worms. Our results suggest that neurotransmitter regulation plays a role in habituation and may play a role in dishabituation."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.20-11-04337.2000"xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.20-11-04337.2000"xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/author | "Rankin C.H."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/author | "Rankin C.H."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/author | "Wicks S.R."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/author | "Wicks S.R."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/name | "J. Neurosci."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/name | "J. Neurosci."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/pages | "4337-4344"xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/pages | "4337-4344"xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/title | "Mutations of the caenorhabditis elegans brain-specific inorganic phosphate transporter eat-4 affect habituation of the tap-withdrawal response without affecting the response itself."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/title | "Mutations of the caenorhabditis elegans brain-specific inorganic phosphate transporter eat-4 affect habituation of the tap-withdrawal response without affecting the response itself."xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/volume | "20"xsd:string |
http://purl.uniprot.org/citations/10818169 | http://purl.uniprot.org/core/volume | "20"xsd:string |
http://purl.uniprot.org/citations/10818169 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10818169 |
http://purl.uniprot.org/citations/10818169 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10818169 |
http://purl.uniprot.org/citations/10818169 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10818169 |
http://purl.uniprot.org/citations/10818169 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10818169 |
http://purl.uniprot.org/uniprot/P34644 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10818169 |
http://purl.uniprot.org/uniprot/P34644#attribution-6CA663DBBF315AEAB4D73CD137F0D382 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10818169 |