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http://purl.uniprot.org/citations/10833452http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10833452http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10833452http://www.w3.org/2000/01/rdf-schema#comment"We have cloned a cDNA that codes for mouse liver-specific transporter-1, mouse lst-1. The cDNA is comprised of 3296 base pairs and it contains a coding sequence for a protein of 689 amino acids with 12 putative transmembrane domains. The deduced amino acid sequence of the mouse lst-1 shares 64 and 77% identities with the reported human and rat lsts, respectively. Northern blot analysis demonstrates that mouse lst-1 mRNA is expressed exclusively in liver. We also report here the structural organization of the mouse lst-1 gene as the first evidence for the structure of a gene encoding an lst. The mouse lst-1 gene spans approximately 60 kbp in length and consists of 16 exons, including two noncoding exons. All the introns are flanked by GT-AG consensus splice sequences. 5'-Rapid Amplification of cDNA Ends (RACE) analyses demonstrate three splice variant mRNAs involving the noncoding exon 2 and exon 3. The 5'-flanking region of the gene contains consensus CAAT and TATA boxes and several potential binding sites for transcription factors for CAAT enhancer binding protein (C/EBP) and hepatocyte nuclear factors (HNF-3beta, HFH-1, and HFH-2), transcription factors important for liver-specific gene expression."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.2000.2830"xsd:string
http://purl.uniprot.org/citations/10833452http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.2000.2830"xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/author"Ogura K."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/author"Ogura K."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/author"Klaassen C.D."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/author"Klaassen C.D."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/author"Choudhuri S."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/author"Choudhuri S."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/pages"563-570"xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/pages"563-570"xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/title"Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1)."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/title"Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1)."xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/volume"272"xsd:string
http://purl.uniprot.org/citations/10833452http://purl.uniprot.org/core/volume"272"xsd:string
http://purl.uniprot.org/citations/10833452http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10833452
http://purl.uniprot.org/citations/10833452http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10833452
http://purl.uniprot.org/citations/10833452http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10833452
http://purl.uniprot.org/citations/10833452http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10833452