| http://purl.uniprot.org/citations/10838081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10838081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10838081 | http://www.w3.org/2000/01/rdf-schema#comment | "Hic-5 is a CAKbeta-binding protein localized at focal adhesions. Here we show that overexpression of CAKbeta or Fyn, but not FAK, enhanced the tyrosine phosphorylation of coexpressed Hic-5 in COS-7 cells. These phosphorylations were further augmented by stimulating cells with osmotic stress. The Y60F mutant of Hic-5 was not phosphorylated, and Hic-5 phosphorylated on tyrosine 60 was bound specifically to the SH2 domain of Csk. Coexpression experiments revealed that the phosphorylation of Hic-5 by CAKbeta required the kinase activation of CAKbeta and binding of Hic-5 by CAKbeta. Specific phosphorylation of Hic-5 by CAKbeta and Fyn may activate a signaling pathway mediated by Hic-5."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(00)01597-0"xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(00)01597-0"xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Sasaki T."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Sasaki T."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Suzuki R."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Suzuki R."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Ishino M."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Ishino M."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Aoto H."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Aoto H."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Sasaski H."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/author | "Sasaski H."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/pages | "179-183"xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/pages | "179-183"xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/title | "Phosphorylation of Hic-5 at tyrosine 60 by CAKbeta and Fyn."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/title | "Phosphorylation of Hic-5 at tyrosine 60 by CAKbeta and Fyn."xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/volume | "474"xsd:string |
| http://purl.uniprot.org/citations/10838081 | http://purl.uniprot.org/core/volume | "474"xsd:string |