RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10839359http://www.w3.org/2000/01/rdf-schema#comment"Sciatic nerve axons in cyclin D1 knockout mice develop normally, become properly ensheathed by Schwann cells, and appear to function normally. However, in the Wallerian degeneration model of nerve injury, the mitotic response of Schwann cells is completely inhibited. The mitotic block is Schwann cell autonomous and developmentally regulated. Rescue analysis (by "knockin" of cyclin E) indicates that D1 protein, rather than regulatory elements of the D1 gene, provides the essential Schwann cell function. Genetic inhibition of the Schwann cell cycle shows that neuronal responses to nerve injury are surprisingly independent of Schwann cell mitotic responses. Even axonal regrowth into the distal zone of a nerve crush injury is not markedly impaired in cyclin D1-/- mice."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)81173-3"xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Roberts T.M."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Kim H.A."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Pomeroy S.L."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Benowitz L.I."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Stiles C.D."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Sicinski P."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Pawlitzky I."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/author"Whoriskey W."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/pages"405-416"xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/title"A developmentally regulated switch directs regenerative growth of Schwann cells through cyclin D1."xsd:string
http://purl.uniprot.org/citations/10839359http://purl.uniprot.org/core/volume"26"xsd:string
http://purl.uniprot.org/citations/10839359http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10839359
http://purl.uniprot.org/citations/10839359http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10839359
http://purl.uniprot.org/uniprot/#_A0A0J9YU51-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359
http://purl.uniprot.org/uniprot/#_B2M0W7-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359
http://purl.uniprot.org/uniprot/#_P25322-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359
http://purl.uniprot.org/uniprot/#_P30280-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359
http://purl.uniprot.org/uniprot/#_Q4FK45-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359
http://purl.uniprot.org/uniprot/#_Q3TC96-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359
http://purl.uniprot.org/uniprot/#_Q790L7-mappedCitation-10839359http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10839359