http://purl.uniprot.org/citations/10841574 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10841574 | http://www.w3.org/2000/01/rdf-schema#comment | "A prospective study of high-risk commercial sex workers in Senegal has shown that HIV-2 infection may reduce the risk of subsequent HIV-1 infection; these findings have been confirmed and extended, now with 13 years of observation. While exploring the biological mechanisms behind this natural protection, we found that a significant proportion of peripheral blood mononuclear cells obtained from HIV-2-infected subjects resisted in vitro challenge with CCR5-dependent HIV-1 viruses but not CXCR4-dependent viruses. High levels of beta-chemokines, the natural ligands of the CCR5 coreceptor, were correlated with low levels of viral replication, and resistance was abrogated by antibodies to beta-chemokines. Our results suggest that beta-chemokine-mediated resistance may be an important correlate of HIV protection against HIV-1 infection and relevant to HIV vaccine design."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.97.12.6797"xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Schwartz D."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Mboup S."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Kokkotou E.G."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Mani I."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Gueye-Ndiaye A."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Kanki P.J."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Sankale J.L."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/author | "Essex M.E."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/pages | "6797-6802"xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/title | "In vitro correlates of HIV-2-mediated HIV-1 protection."xsd:string |
http://purl.uniprot.org/citations/10841574 | http://purl.uniprot.org/core/volume | "97"xsd:string |
http://purl.uniprot.org/citations/10841574 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10841574 |
http://purl.uniprot.org/citations/10841574 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10841574 |
http://purl.uniprot.org/uniprot/P10147#attribution-05CE0DE4448EBB3309770FA4CDBF37E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10841574 |
http://purl.uniprot.org/uniprot/P13501#attribution-05CE0DE4448EBB3309770FA4CDBF37E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10841574 |
http://purl.uniprot.org/uniprot/P13236#attribution-05CE0DE4448EBB3309770FA4CDBF37E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10841574 |