| http://purl.uniprot.org/citations/10882135 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10882135 | http://www.w3.org/2000/01/rdf-schema#comment | "Cdc20, an activator of the anaphase-promoting complex (APC), is also required for the exit from mitosis in Saccharomyces cerevisiae. Here we show that during mitosis, both the inactivation of Cdc28-Clb2 kinase and the degradation of mitotic cyclin Clb2 occur in two steps. The first phase of Clb2 proteolysis, which commences at the metaphase-to-anaphase transition when Clb2 abundance is high, is dependent on Cdc20. The second wave of Clb2 destruction in telophase requires activation of the Cdc20 homolog, Hct1/Cdh1. The first phase of Clb2 destruction, which lowers the Cdc28-Clb2 kinase activity, is a prerequisite for the second. Thus, Clb2 proteolysis is not solely mediated by Hct1 as generally believed; instead, it requires a sequential action of both Cdc20 and Hct1."xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80444-x"xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/author | "Lim H.H."xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/author | "Surana U."xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/author | "Yeong F.M."xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/author | "Padmashree C.G."xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/name | "Mol Cell"xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/pages | "501-511"xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/title | "Exit from mitosis in budding yeast: biphasic inactivation of the Cdc28-Clb2 mitotic kinase and the role of Cdc20."xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/10882135 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10882135 |
| http://purl.uniprot.org/citations/10882135 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10882135 |
| http://purl.uniprot.org/uniprot/#_P00546-mappedCitation-10882135 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/#_P26309-mappedCitation-10882135 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/#_P24869-mappedCitation-10882135 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/#_P53197-mappedCitation-10882135 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/P26309 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/P24869 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/P00546 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10882135 |
| http://purl.uniprot.org/uniprot/P53197 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10882135 |