| http://purl.uniprot.org/citations/10931310 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10931310 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10931310 | http://www.w3.org/2000/01/rdf-schema#comment | "Among enteric bacteria, the ability to grow on N-acetyl-galactosamine (GalNAc or Aga) and on D-galactosamine (GalN or Gam) differs. Thus, strains B, C and EC3132 of Escherichia coli are Aga+ Gam+ whereas E. coli K-12 is Aga-Gam-, similarly to Klebsiella pneumoniae KAY2026, Klebsiella oxytoca M5a1 and Salmonella typhimurium LT2. The former strains carry a complete aga/kba gene cluster at 70.5 min of their gene map. These genes encode an Aga-specific phosphotransferase system (PTS) or IIAga (agaVWE) and a GalN-specific PTS or IIGam (agaBCD). Both PTSs belong to the mannose-sorbose family, i.e. the IIB, IIC and IID domains are encoded by different genes, and they share a IIA domain (agaF). Furthermore, the genes encode an Aga6P-deacetylase (agaA), a GalN6P deaminase (agaI), a tagatose-bisphosphate aldolase comprising two different peptides (kbaYZ) and a putative isomerase (agaS), i.e. complete pathways for the transport and degradation of both amino sugars. The genes are organized in two adjacent operons (kbaZagaVWEFA and agaS kbaYagaBCDI) and controlled by a repressor AgaR. Its gene agaR is located upstream of kbaZ, and AgaR responds to GalNAc and GalN in the medium. All Aga- Gam-strains, however, carry a deletion covering genes agaW' EF 'A; consequently they lack active IIAga and IIGam PTSs, thus explaining their inability to grow on the two amino sugars. Remnants of a putative recombination site flank the deleted DNA in the various Aga- Gam- enteric bacteria. Derivatives with an Aga+ Gam-phenotype can be isolated from E. coli K-12. These retain the DeltaagaW' EF 'A deletion and carry suppressor mutations in the gat and nag genes for galactitol and N-acetyl-glucosamine metabolism, respectively, that allow growth on Aga but not on GalN."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2000.01969.x"xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2000.01969.x"xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Alpert C.-A."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Alpert C.-A."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Brinkkoetter A."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Brinkkoetter A."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Kloess H."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Kloess H."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Lengeler J.W."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/author | "Lengeler J.W."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/pages | "125-135"xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/pages | "125-135"xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/title | "Pathways for the utilization of N-acetyl-galactosamine and galactosamine in Escherichia coli."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/title | "Pathways for the utilization of N-acetyl-galactosamine and galactosamine in Escherichia coli."xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/10931310 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10931310 |
| http://purl.uniprot.org/citations/10931310 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10931310 |