http://purl.uniprot.org/citations/10939335 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10939335 | http://www.w3.org/2000/01/rdf-schema#comment | "Compartmentalization of glutamate receptors with the signaling enzymes that regulate their activity supports synaptic transmission. Two classes of binding proteins organize these complexes: the MAGUK proteins that cluster glutamate receptors and AKAPs that anchor kinases and phosphatases. In this report, we demonstrate that glutamate receptors and PKA are recruited into a macromolecular signaling complex through direct interaction between the MAGUK proteins, PSD-95 and SAP97, and AKAP79/150. The SH3 and GK regions of the MAGUKs mediate binding to the AKAP. Cell-based studies indicate that phosphorylation of AMPA receptors is enhanced by a SAP97-AKAP79 complex that directs PKA to GluR1 via a PDZ domain interaction. As AMPA receptor phosphorylation is implicated in regulating synaptic plasticity, these data suggest that a MAGUK-AKAP complex may be centrally involved."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)00013-1"xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/author | "Dean R.A."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/author | "Scott J.D."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/author | "Huganir R.L."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/author | "Langeberg L.K."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/author | "Scott G.K."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/author | "Colledge M."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/pages | "107-119"xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/title | "Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex."xsd:string |
http://purl.uniprot.org/citations/10939335 | http://purl.uniprot.org/core/volume | "27"xsd:string |
http://purl.uniprot.org/citations/10939335 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10939335 |
http://purl.uniprot.org/citations/10939335 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10939335 |
http://purl.uniprot.org/uniprot/P24588#attribution-5DE6A2F930D1BAEF52058B7E02B05A34 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P24588#attribution-A7710D717CAECCA14AD1D3135C168C95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P24587#attribution-5D85964B7F8B5A5B43A94564B4591E6C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P24587#attribution-5DE6A2F930D1BAEF52058B7E02B05A34 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P24587#attribution-A7710D717CAECCA14AD1D3135C168C95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P24587#attribution-A7C1F07A2A90800D1E9DEA2182B16807 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P31016#attribution-5DE6A2F930D1BAEF52058B7E02B05A34 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P19490#attribution-5DE6A2F930D1BAEF52058B7E02B05A34 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |
http://purl.uniprot.org/uniprot/P19490#attribution-A7710D717CAECCA14AD1D3135C168C95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10939335 |