| http://purl.uniprot.org/citations/10944456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10944456 | http://www.w3.org/2000/01/rdf-schema#comment | "In this study we demonstrate that the rat pheochromocytoma PC12 cell line expresses the novel protein kinase C isozyme designated PKC-θ. The isozyme is almost completely localized in the nuclear compartment of proliferating cells. Following stimulation with the nerve growth factor, PKC-θ is redistributed into the cytoplasm and the outgrowing neurite processes, mostly as a cytoskeletal associated kinase. This event is accompanied by an eightfold increase in the expression level and by the appearance of specific modifications of PKC-θ molecule. Conversely, the kinase is down-regulated once cells reach the terminally differentiated state displaying a neuron-like phenotype. These data suggest a functional role for the kinase in the regulation of cytoskeletal modeling along the multistage differentiation process of PC12 cells."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.3258"xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/author | "Patrone M."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/author | "Melloni E."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/author | "Pontremoli S."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/author | "Sparatore B."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/author | "Pedrazzi M."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/author | "Passalacqua M."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/pages | "149-153"xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/title | "Neuronal differentiation of PC12 cells involves changes in protein kinase C-theta distribution and molecular properties."xsd:string |
| http://purl.uniprot.org/citations/10944456 | http://purl.uniprot.org/core/volume | "275"xsd:string |
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| http://purl.uniprot.org/citations/10944456 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10944456 |
| http://purl.uniprot.org/uniprot/Q9WTQ0#attribution-AAB6EC9ECBF612C589D8CE309163031A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10944456 |
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| http://purl.uniprot.org/uniprot/#_Q9WTQ0-mappedCitation-10944456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10944456 |
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