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http://purl.uniprot.org/citations/10950931http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10950931http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10950931http://www.w3.org/2000/01/rdf-schema#comment"We have cloned cDNA for TTYH1, a human homologue of the Drosophila melanogaster tweety (tty) gene. The 450-residue predicted protein shows 27% amino acid sequence identity (51% similarity) to the Drosophila protein, which contains an additional C-terminal repetitive region. A second Drosophila homologue exhibits 42% identity (65% similarity) to the tty protein. Mouse (Ttyh1), macaque, and Caenorhabditis elegans homologues were also identified, and the complete coding sequence for the mouse gene was determined. The mouse protein is 91% identical to the human protein. Hydrophobicity analysis of the tty-related proteins indicates that they represent a new family of membrane proteins with five potential membrane-spanning regions. The yeast FTR1 and FTH1 iron transporter proteins and the mammalian neurotensin receptors 1 and 2 have a similar hydrophobicity profile, although there is no detectable sequence homology to the tty-related proteins. This suggests that the tweety-related proteins could be involved in transport of iron or other divalent cations or alternatively that they may be membrane-bound receptors. TTYH1 was mapped to chromosome 19q13.4 by FISH and by radiation hybrid mapping using the Stanford G3 panel."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.org/dc/terms/identifier"doi:10.1006/geno.2000.6259"xsd:string
http://purl.uniprot.org/citations/10950931http://purl.org/dc/terms/identifier"doi:10.1006/geno.2000.6259"xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Hida M."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Hida M."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Sugano S."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Sugano S."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Suzuki Y."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Suzuki Y."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Sutherland G.R."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Sutherland G.R."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Woollatt E."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Woollatt E."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Kamei M."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Kamei M."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Campbell H.D."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Campbell H.D."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Young I.G."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Young I.G."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Claudianos C."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/author"Claudianos C."xsd:string
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10950931http://purl.uniprot.org/core/date"2000"xsd:gYear