| http://purl.uniprot.org/citations/10953877 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10953877 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10953877 | http://www.w3.org/2000/01/rdf-schema#comment | "The Kluyveromyces lactis UBP2 gene was isolated as a suppressor of a temperature-sensitive mutation in CBF2, a gene coding for a centromere-binding protein of Saccharomyces cerevisiae. The UBP genes are hydrolases than can cleave a ubiquitin moiety from a protein substrate. KlUBP2 is not essential for growth since a disruption of the KlUBP2 gene had little effect, except for a slight decrease in the growth rate. The stability of centromere-containing plasmids was not influenced either. In addition to KlUBP2, five S. cerevisiae genes involved in the ubiquitination pathway could suppress the ts-mutation in the CBF2 gene, namely UBA1, UBA2, UBP1, UBP2 and YUH1, although YUH1 was the only one that could do this like KlUBP2 from a single-copy plasmid. Surprisingly, these genes encode proteins with antagonistic activity as two, UBA1 and UBA2, are ubiquitin-activating enzymes whereas the other three are de-ubiquitinating hydrolases."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.org/dc/terms/identifier | "doi:10.1007/s002940000129"xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.org/dc/terms/identifier | "doi:10.1007/s002940000129"xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Steensma H.Y."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Steensma H.Y."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Hooykaas P.J.J."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Hooykaas P.J.J."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Korstanje R."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Korstanje R."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Winkler A.A."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Winkler A.A."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Zonneveld B.J.M."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/author | "Zonneveld B.J.M."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/name | "Curr. Genet."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/name | "Curr. Genet."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/pages | "17-22"xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/pages | "17-22"xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/title | "Isolation and characterization of KIUBP2, a ubiquitin hydrolase gene of Kluyveromyces lactis that can suppress a ts-mutation in CBF2, a gene encoding a centromeric protein of Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/title | "Isolation and characterization of KIUBP2, a ubiquitin hydrolase gene of Kluyveromyces lactis that can suppress a ts-mutation in CBF2, a gene encoding a centromeric protein of Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/volume | "38"xsd:string |
| http://purl.uniprot.org/citations/10953877 | http://purl.uniprot.org/core/volume | "38"xsd:string |