| http://purl.uniprot.org/citations/10956646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10956646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10956646 | http://www.w3.org/2000/01/rdf-schema#comment | "An expression cloning approach was employed to identify the receptor for B-lymphocyte stimulator (BLyS) and identified the tumor necrosis factor receptor superfamily member TACI as a BLyS-binding protein. Expression of TACI in HEK293T cells confers on the cells the ability to bind BLyS with subnanomolar affinity. Furthermore, a TACI-Fc fusion protein recognizes both the cleaved, soluble form of BLyS as well as the membrane BLyS present on the cell surface of a recombinant cell line. TACI mRNA is found predominantly in B-cells and correlates with BLyS binding in a panel of B-cell lines. We also demonstrate that TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. BLyS and APRIL are capable of signaling through TACI to mediate NF-kappaB responses in HEK293 cells. We conclude that TACI is a receptor for BLyS and APRIL and discuss the implications for B-cell biology."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m005224200"xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m005224200"xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Feng P."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Feng P."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Gan Y."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Gan Y."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Taylor K."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Taylor K."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Wei P."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Wei P."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Cho Y.H."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Cho Y.H."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Garcia A.D."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Garcia A.D."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Kanakaraj P."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Kanakaraj P."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Moore P.A."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Moore P.A."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Nardelli B."xsd:string |
| http://purl.uniprot.org/citations/10956646 | http://purl.uniprot.org/core/author | "Nardelli B."xsd:string |