| http://purl.uniprot.org/citations/10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10973281 | http://www.w3.org/2000/01/rdf-schema#comment | "Tapasin is a component of the major histocompatibility complex (MHC) class I antigen-loading complex. Here we show that mice with a disrupted tapasin gene display reduced MHC class I expression. Cytotoxic T cell (CTL) responses to viruses are impaired, and dendritic cells of tapasin-deficient mice do not cross-present protein antigen via the MHC class I pathway, indicating a defect in antigen processing. Natural killer (NK) cells from tapasin-deficient mice have an altered repertoire and are self-tolerant. In addition, the repertoire of class I-bound peptides is altered towards less stably binding ones. Thus tapasin plays a role in CTL and NK immune responses and in optimal peptide selection."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.org/dc/terms/identifier | "doi:10.1038/79775"xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Tan P."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Ljunggren H.G."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Chambers B.J."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Momburg F."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Hammerling G.J."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Garbi N."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/author | "Diehl A.D."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/pages | "234-238"xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/title | "Impaired immune responses and altered peptide repertoire in tapasin-deficient mice."xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://purl.uniprot.org/core/volume | "1"xsd:string |
| http://purl.uniprot.org/citations/10973281 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10973281 |
| http://purl.uniprot.org/citations/10973281 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10973281 |
| http://purl.uniprot.org/uniprot/#_A0A068BER1-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_A0A068BIS1-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_A0A3Q4EGL0-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_A0A3Q4L2T5-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_G3UZZ2-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_F6QHF1-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_Q3U543-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |
| http://purl.uniprot.org/uniprot/#_Q62428-mappedCitation-10973281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10973281 |