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http://purl.uniprot.org/citations/10974554http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10974554http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10974554http://www.w3.org/2000/01/rdf-schema#comment"Murine Gtse-1 (G(2) and S phase expressed protein), previously named B99, is a wt-p53 inducible gene that encodes a microtubule-localized protein which is able to induce G(2)/M phase accumulation when ectopically expressed. Here we report the cloning and characterization of a new cDNA (GTSE-1) encoding a human homologue of the mouse Gtse-1 protein. Chromosome mapping of mouse and human genes assigned Gtse-1 to chromosome 15 and GTSE-1 to chromosome 22q13.2-q13.3 in a region with conserved synteny to that where Gtse-1 mapped. Analysis of the genomic structure revealed that GTSE-1 contains at least 11 exons and 10 introns, spanning approximately 33kb of genomic DNA. Similar to murine Gtse-1, the product of GTSE-1 localized to the microtubules, was able to delay G(2)/M progression when ectopically expressed and was cell cycle regulated. Taken together, these results indicate GTSE-1 as the human functional homologue of murine Gtse-1."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(00)00260-2"xsd:string
http://purl.uniprot.org/citations/10974554http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(00)00260-2"xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Lazarevic D."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Lazarevic D."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Schneider C."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Schneider C."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Dragani T.A."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Dragani T.A."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Collavin L."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Collavin L."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Monte M."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Monte M."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Utrera R."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/author"Utrera R."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/pages"229-236"xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/pages"229-236"xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/title"Cloning, chromosome mapping and functional characterization of a human homologue of murine Gtse-1 (B99) gene."xsd:string
http://purl.uniprot.org/citations/10974554http://purl.uniprot.org/core/title"Cloning, chromosome mapping and functional characterization of a human homologue of murine Gtse-1 (B99) gene."xsd:string