| http://purl.uniprot.org/citations/10978280 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10978280 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10978280 | http://www.w3.org/2000/01/rdf-schema#comment | "Sensory cues regulate several aspects of behavior and development in Caenorhabditis elegans, including entry into and exit from an alternative developmental stage called the dauer larva. Three parallel pathways, including a TGF-beta-like pathway, regulate dauer formation. The mechanisms by which the activities of these pathways are regulated by sensory signals are largely unknown. The gene egl-4 was initially identified based on its egg-laying defects. We show here that egl-4 has many pleiotropies, including defects in chemosensory behavior, body size, synaptic transmission, and dauer formation. Our results are consistent with a role for egl-4 in relaying sensory cues to multiple behavioral and developmental circuits in C. elegans. By epistasis analysis, we also place egl-4 in the TGF-beta-like branch and show that a SMAD gene functions downstream of egl-4 in multiple egl-4-regulated pathways, including chemosensation."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/156.1.123"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/156.1.123"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Sengupta P."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Sengupta P."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Ailion M."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Ailion M."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Thomas J.H."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Thomas J.H."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Daniels S.A."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/author | "Daniels S.A."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/pages | "123-141"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/pages | "123-141"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/title | "egl-4 acts through a transforming growth factor-beta/SMAD pathway in Caenorhabditis elegans to regulate multiple neuronal circuits in response to sensory cues."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/title | "egl-4 acts through a transforming growth factor-beta/SMAD pathway in Caenorhabditis elegans to regulate multiple neuronal circuits in response to sensory cues."xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/volume | "156"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://purl.uniprot.org/core/volume | "156"xsd:string |
| http://purl.uniprot.org/citations/10978280 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10978280 |
| http://purl.uniprot.org/citations/10978280 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10978280 |