http://purl.uniprot.org/citations/10981963 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10981963 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10981963 | http://www.w3.org/2000/01/rdf-schema#comment | "BCL-6, a transcriptional repressor frequently translocated in lymphomas, regulates germinal center B cell differentiation and inflammation. DNA microarray screening identified genes repressed by BCL-6, including many lymphocyte activation genes, suggesting that BCL-6 modulates B cell receptor signals. BCL-6 repression of two chemokine genes, MIP-1alpha and IP-10, may also attenuate inflammatory responses. Blimp-1, another BCL-6 target, is important for plasmacytic differentiation. Since BCL-6 expression is silenced in plasma cells, repression of blimp-1 by BCL-6 may control plasmacytic differentiation. Indeed, inhibition of BCL-6 function initiated changes indicative of plasmacytic differentiation, including decreased expression of c-Myc and increased expression of the cell cycle inhibitor p27kip1. These data suggest that malignant transformation by BCL-6 involves inhibition of differentiation and enhanced proliferation."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)00020-0"xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)00020-0"xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "He Y."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "He Y."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Staudt L.M."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Staudt L.M."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Shaffer A.L."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Shaffer A.L."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Boldrick J."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Boldrick J."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Chan E.P."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/author | "Chan E.P."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/pages | "199-212"xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/pages | "199-212"xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/title | "BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control."xsd:string |
http://purl.uniprot.org/citations/10981963 | http://purl.uniprot.org/core/title | "BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control."xsd:string |