RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11010837http://www.w3.org/2000/01/rdf-schema#comment"Host genetic factors, such as HLA alleles, are important in human immunodeficiency virus (HIV) infection and its progression to AIDS. HLA class I gene products are involved in peptide presentation, and each allele is responsible for presenting a different set of peptides to cytotoxic T lymphocytes. The increase or decrease in the frequency of certain alleles in HIV-1-positive versus control subjects would suggest that alleles play a role in susceptibility to or protection against this viral infection. In the present study, 56 HIV-1-positive patients in Chaco Province, Argentina, were typed for the HLA-A and HLA-B loci, using polymerase chain reaction and sequence-specific oligonucleotide probes. The frequency of alleles A*24, B*18, and B*39 was increased in HIV-1-positive subjects, suggesting that these alleles play a role in susceptibility to HIV-1 infection. Alleles B*44 and B*55 were not found in HIV-1-positive subjects, suggesting that they have a protective effect against the disease. The P values of the alleles B*39 and B*44 were statistically significant (P<.05)."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.org/dc/terms/identifier"doi:10.1086/315854"xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/author"Lopez R."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/author"Sorrentino A."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/author"Motta P."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/author"Marinic K."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/author"Illiovich E."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/author"de Sorrentino A.H."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/name"J Infect Dis"xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/pages"1523-1526"xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/title"HLA class I alleles associated with susceptibility or resistance to human immunodeficiency virus type 1 infection among a population in Chaco Province, Argentina."xsd:string
http://purl.uniprot.org/citations/11010837http://purl.uniprot.org/core/volume"182"xsd:string
http://purl.uniprot.org/citations/11010837http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11010837
http://purl.uniprot.org/citations/11010837http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11010837
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0G2R0N3-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0G2R0N4-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837
http://purl.uniprot.org/uniprot/#_A0A0G2R0N5-mappedCitation-11010837http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11010837