http://purl.uniprot.org/citations/11027612 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11027612 | http://www.w3.org/2000/01/rdf-schema#comment | "Ganglioside GD3 induced the release of cytochrome c from isolated rat liver mitochondria. This process was completely prevented by cyclosporin A and partially prevented by a cysteine protease inhibitor, n-acetyl-leu-leu-norleucinal. Cyclosporin A is a potent inhibitor of the permeability transition pore, whereas n-acetyl-leu-leu-norleucinal has no effect on this pore. These results indicate that the release of cytochrome c from mitochondria requires both the opening of the permeability transition pore and a cysteine protease inhibitor-sensitive mechanism. Gangliosides GD1a, GD1b, GT1b, and GQ1b along with the synthetic GD3 mimetics TMS-42 and CI-22, which are glycerophospholipids carrying a disialo residue, also induced cytochrome c release. In contrast, gangliosides GM1, GM2, and GM3 did not induce cytochrome c release. These results indicate that two sialo residues must play an important role in the induction of cytochrome c release by gangliosides."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.3601"xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Miura T."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Yoshida Y."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Inoki Y."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Kawase M."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Hamamoto T."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Kagawa Y."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Tsuji S."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Endo H."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Kinouchi T."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Kawase Y."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/author | "Kajimoto T."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/pages | "1210-1216"xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/title | "Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria."xsd:string |
http://purl.uniprot.org/citations/11027612 | http://purl.uniprot.org/core/volume | "276"xsd:string |
http://purl.uniprot.org/citations/11027612 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11027612 |
http://purl.uniprot.org/citations/11027612 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11027612 |
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http://purl.uniprot.org/uniprot/#_P62898-mappedCitation-11027612 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11027612 |
http://purl.uniprot.org/uniprot/A0A8I5Y1A4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11027612 |
http://purl.uniprot.org/uniprot/P62898 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11027612 |