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http://purl.uniprot.org/citations/11027612http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11027612http://www.w3.org/2000/01/rdf-schema#comment"Ganglioside GD3 induced the release of cytochrome c from isolated rat liver mitochondria. This process was completely prevented by cyclosporin A and partially prevented by a cysteine protease inhibitor, n-acetyl-leu-leu-norleucinal. Cyclosporin A is a potent inhibitor of the permeability transition pore, whereas n-acetyl-leu-leu-norleucinal has no effect on this pore. These results indicate that the release of cytochrome c from mitochondria requires both the opening of the permeability transition pore and a cysteine protease inhibitor-sensitive mechanism. Gangliosides GD1a, GD1b, GT1b, and GQ1b along with the synthetic GD3 mimetics TMS-42 and CI-22, which are glycerophospholipids carrying a disialo residue, also induced cytochrome c release. In contrast, gangliosides GM1, GM2, and GM3 did not induce cytochrome c release. These results indicate that two sialo residues must play an important role in the induction of cytochrome c release by gangliosides."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.2000.3601"xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Miura T."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Yoshida Y."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Inoki Y."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Kawase M."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Hamamoto T."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Kagawa Y."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Tsuji S."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Endo H."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Kinouchi T."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Kawase Y."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/author"Kajimoto T."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/pages"1210-1216"xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/title"Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria."xsd:string
http://purl.uniprot.org/citations/11027612http://purl.uniprot.org/core/volume"276"xsd:string
http://purl.uniprot.org/citations/11027612http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11027612
http://purl.uniprot.org/citations/11027612http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11027612
http://purl.uniprot.org/uniprot/#_A0A8I5Y1A4-mappedCitation-11027612http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11027612
http://purl.uniprot.org/uniprot/#_P62898-mappedCitation-11027612http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11027612
http://purl.uniprot.org/uniprot/A0A8I5Y1A4http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/11027612
http://purl.uniprot.org/uniprot/P62898http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/11027612