http://purl.uniprot.org/citations/11027668 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11027668 | http://www.w3.org/2000/01/rdf-schema#comment | "A new 55-kDa HDL/apolipoprotein binding protein was demonstrated in plasma membrane preparations of the human cell lines and primary cultured hepatocytes. Analysis of specific binding by ligand immunoblots of HDL, apoA-I, and apoA-II to a partially purified 55-kDa PA-I plasma membrane preparation demonstrated a K(d,HDL) = 50 nM (10 microg/ml), K(d,apoA-II) = 20 nM (0.4 microg/ml), and K(d, apoA-I) = 330 nM (10 microg/ml). Following preparative SDS-PAGE electrophoresis of a plasma membrane preparation isolated from human PA-I cells, fractions with apoA-II binding activity were collected, concentrated, and subjected to two-dimensional electrophoresis. Internal microprotein sequencing of the 55-kDa protein band revealed the binding protein as being heat shock protein 60 (hsp60). The hsp60 monoclonal antibody LK-1 blocked apoA-II binding to the 55-kDa HBP preparation. In summary, these results provide a potential mechanism to explain the known association between immunity developed against hsp60 and the development of atherosclerosis."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.3663"xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/author | "Remaley A.T."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/author | "Patterson A.P."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/author | "Bocharov A.V."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/author | "Baranova I.N."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/author | "Eggerman T.L."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/author | "Vishnyakova T.G."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/pages | "228-235"xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/title | "Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein."xsd:string |
http://purl.uniprot.org/citations/11027668 | http://purl.uniprot.org/core/volume | "277"xsd:string |
http://purl.uniprot.org/citations/11027668 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11027668 |
http://purl.uniprot.org/citations/11027668 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11027668 |
http://purl.uniprot.org/uniprot/P02647#attribution-DBE563E46F3698953A43D7C8BD63DAEA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11027668 |
http://purl.uniprot.org/uniprot/P02652#attribution-DBE563E46F3698953A43D7C8BD63DAEA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11027668 |
http://purl.uniprot.org/uniprot/P10809#attribution-DBE563E46F3698953A43D7C8BD63DAEA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11027668 |
http://purl.uniprot.org/uniprot/P10809#attribution-EB37694B4A321A478100798A55440398 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11027668 |