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http://purl.uniprot.org/citations/11030746http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11030746http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11030746http://www.w3.org/2000/01/rdf-schema#comment"A novel form of murine beta-1,6-N:-acetylglucosaminyltransferase that forms branches in poly-N:-acetyllactosamines (designated as IGnT B) was cloned based on sequence homology to the known IGnT (designated as IGnT A). When expressed as proteins, IGnT B showed higher specific activity than IGnT A. The C-terminal 1/4 of IGnT B was identical to that of IGnT A, while the rest of the predicted sequences showed 63% identity. Genomic analysis indicated that IGnT A and IGnT B were derived by alternative splicing; the unique portion was encoded by exon 1, and the common portion was encoded by exons 2 and 3. IGnT B showed an expression profile closely related to that of IGnT A and was strongly expressed in the liver, kidney and intestine, and moderately in the mammary gland, submaxially gland, embryonic stem cells, and embryonal carcinoma cells. The specificity of IGnT B examined using various substrates was indistinguishable from that of IGnT A, which is classified as the central acting IGnT (cIGnT). Thus, IGnT B acted on Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc, but not on GlcNAcbeta1-3Galbeta1-4Glc. It formed branches in both of the internal galactosyl residues of Galbeta1-4Glc-NAcbeta1-3Galbeta1-4GlcNAcbeta1-++ +3Galbeta1-4Glc, and prolonged incubation resulted in production of the di-branched oligosaccharide. Although addition of sialic acid to the terminal galactosyl residue did not abolish the acceptor activity, alpha2-6 sialylation was a preferred one as compared to alpha2-3 sialylation."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.org/dc/terms/identifier"doi:10.1093/glycob/10.10.1001"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.org/dc/terms/identifier"doi:10.1093/glycob/10.10.1001"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/author"Kurosawa N."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/author"Kurosawa N."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/author"Muramatsu T."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/author"Muramatsu T."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/author"Chen G.Y."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/author"Chen G.Y."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/name"Glycobiology"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/name"Glycobiology"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/pages"1001-1011"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/pages"1001-1011"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/title"A novel variant form of murine beta-1, 6-N-acetylglucosaminyltransferase forming branches in poly-N-acetyllactosamines."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/title"A novel variant form of murine beta-1, 6-N-acetylglucosaminyltransferase forming branches in poly-N-acetyllactosamines."xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/11030746http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/11030746http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11030746
http://purl.uniprot.org/citations/11030746http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11030746
http://purl.uniprot.org/citations/11030746http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11030746
http://purl.uniprot.org/citations/11030746http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11030746