| http://purl.uniprot.org/citations/11032397 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11032397 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11032397 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-13 (IL-13) regulates immune responses mediated by type 2 T helper lymphocytes (Th2) in the human and mouse. To study the function of this cytokine in the dog, we have isolated a cDNA that encodes the full-length canine IL-13 (CaIL-13) precursor polypeptide of 131 amino acids. CaIL-13 shares significant homology with the IL-13 amino acid sequences of cattle (54.1%), mouse (39.6%), and rat (36.6%) but shares the highest identity with human IL-13 (HuIL-13) (61.8%). The predicted CaIL-13 mature polypeptide of 111 residues was expressed in bacteria, and recombinant CaIL-13 (rCaIL-13) was isolated from inclusion bodies and refolded. rCaIL-13 stimulated the proliferation of TF-1 cells, which are derived from human erythroleukemia cells and respond to IL-13 as well as to a number of other human and murine cytokines. CaIL-13 mRNA was readily detectable by reverse transcriptase-polymerase chain reaction (RT-PCR) in cells from lymph nodes and peripheral blood. The gene sequence and biologically active recombinant protein for CaIL-13 will be useful reagents to determine the role of IL-13 in the regulation of canine immune responses."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.org/dc/terms/identifier | "doi:10.1089/10799900050151049"xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.org/dc/terms/identifier | "doi:10.1089/10799900050151049"xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/author | "Yang S."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/author | "Yang S."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/author | "McDermott M.J."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/author | "McDermott M.J."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/author | "Boroughs K.L."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/author | "Boroughs K.L."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/name | "J. Interferon Cytokine Res."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/name | "J. Interferon Cytokine Res."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/pages | "779-785"xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/pages | "779-785"xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/title | "Canine interleukin-13: molecular cloning of full-length cDNA and expression of biologically active recombinant protein."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/title | "Canine interleukin-13: molecular cloning of full-length cDNA and expression of biologically active recombinant protein."xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/volume | "20"xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://purl.uniprot.org/core/volume | "20"xsd:string |
| http://purl.uniprot.org/citations/11032397 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11032397 |
| http://purl.uniprot.org/citations/11032397 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11032397 |
| http://purl.uniprot.org/citations/11032397 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11032397 |
| http://purl.uniprot.org/citations/11032397 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11032397 |