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http://purl.uniprot.org/citations/11041879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11041879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11041879http://www.w3.org/2000/01/rdf-schema#comment"We have established an Arabidopsis protoplast model system to study plant cell death signaling. The fungal toxin fumonisin B1 (FB1) induces apoptosis-like programmed cell death (PCD) in wild-type protoplasts. FB1, however, only marginally affects the viability of protoplasts isolated from transgenic NahG plants, in which salicylic acid (SA) is metabolically degraded; from pad4-1 mutant plants, in which an SA amplification mechanism is thought to be impaired; or from jar1-1 or etr1-1 mutant plants, which are insensitive to jasmonate (JA) or ethylene (ET), respectively. FB1 susceptibility of wild-type protoplasts decreases in the dark, as does the cellular content of phenylalanine ammonia-lyase, a light-inducible enzyme involved in SA biosynthesis. Interestingly, however, FB1-induced PCD does not require the SA signal transmitter NPR1, given that npr1-1 protoplasts display wild-type FB1 susceptibility. Arabidopsis cpr1-1, cpr6-1, and acd2-2 protoplasts, in which the SA signaling pathway is constitutively activated, exhibit increased susceptibility to FB1. The cpr6-1 and acd2-2 mutants also constitutively express the JA and ET signaling pathways, but only the acd2-2 protoplasts undergo PCD in the absence of FB1. These results demonstrate that FB1 killing of Arabidopsis is light dependent and requires SA-, JA-, and ET-mediated signaling pathways as well as one or more unidentified factors activated by FB1 and the acd2-2 mutation."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.org/dc/terms/identifier"doi:10.1105/tpc.12.10.1823"xsd:string
http://purl.uniprot.org/citations/11041879http://purl.org/dc/terms/identifier"doi:10.1105/tpc.12.10.1823"xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Ausubel F.M."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Ausubel F.M."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Stone J.M."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Stone J.M."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Sheen J."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Sheen J."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Asai T."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Asai T."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Kovtun Y."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Kovtun Y."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Heard J.E."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Heard J.E."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Yorgey P."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/author"Yorgey P."xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/name"Plant Cell"xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/name"Plant Cell"xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/pages"1823-1836"xsd:string
http://purl.uniprot.org/citations/11041879http://purl.uniprot.org/core/pages"1823-1836"xsd:string