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http://purl.uniprot.org/citations/11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11051549http://www.w3.org/2000/01/rdf-schema#comment"How multifunctional signals combine to specify unique cell fates during pattern formation is not well understood. Here, we demonstrate that together with the transcription factor Lozenge, the nuclear effectors of the EGFR and Notch signaling pathways directly regulate D-Pax2 transcription in cone cells of the Drosophila eye disc. Moreover, the specificity of D-Pax2 expression can be altered upon genetic manipulation of these inputs. Thus, a relatively small number of temporally and spatially controlled signals received by a set of pluripotent cells can create the unique combinations of activated transcription factors required to regulate target genes and ultimately specify distinct cell fates within this group. We expect that similar mechanisms may specify pattern formation in vertebrate developmental systems that involve intercellular communication."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)00106-9"xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Yan H."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Noll M."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Zou Y."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Fu W."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Duan H."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Banerjee U."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Nagaraj R."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/author"Flores G.V."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/pages"75-85"xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/title"Combinatorial signaling in the specification of unique cell fates."xsd:string
http://purl.uniprot.org/citations/11051549http://purl.uniprot.org/core/volume"103"xsd:string
http://purl.uniprot.org/citations/11051549http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11051549
http://purl.uniprot.org/citations/11051549http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11051549
http://purl.uniprot.org/uniprot/#_A4V346-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549
http://purl.uniprot.org/uniprot/#_A8Y4W5-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549
http://purl.uniprot.org/uniprot/#_M9NFP7-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549
http://purl.uniprot.org/uniprot/#_D1YSG9-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549
http://purl.uniprot.org/uniprot/#_P10041-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549
http://purl.uniprot.org/uniprot/#_Q6SAZ6-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549
http://purl.uniprot.org/uniprot/#_Q6SAZ7-mappedCitation-11051549http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11051549