http://purl.uniprot.org/citations/11054540 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11054540 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11054540 | http://www.w3.org/2000/01/rdf-schema#comment | "We have isolated a murine cDNA orthologous to the human matrix metalloproteinase 19 (hMMP-19). The murine MMP-19 cDNA was amplified by RT-PCR using specific primers whose DNA sequences were derived from both murine MMP-19 genomic DNA and partial cDNA sequences. The murine MMP-19 (mMMP-19) is 79% identical to the human ortholog and encodes a protein of 527 amino acids with a deduced molecular mass of 59.1kDa. Analyzing the exon/intron junctions we revealed that the murine MMP-19 gene consists of nine exons and eight introns, and thus differs from the gene organization of other matrix metalloproteinases. Furthermore, a 587bp fragment of the mMMP-19 promoter containing a TATA box and an AP-1 binding motif was cloned, and 3.3kb transcripts of the MMP-19 gene were identified in liver, kidney, spleen, and colon. Finally, immunostaining of murine heart cryosections showed that mMMP-19, like its human counterpart, is expressed in the arterial tunica media of large blood vessels. By cloning mMMP-19 and unraveling its genomic structure, we have obtained valuable information for further study of the function of this MMP in vivo."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(00)00369-3"xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(00)00369-3"xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Mueller M.S."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Mueller M.S."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Sedlacek R."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Sedlacek R."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Kolb C."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Kolb C."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Kusch J."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Kusch J."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Harnasch M."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Harnasch M."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Sadowski T."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/author | "Sadowski T."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/pages | "101-111"xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/pages | "101-111"xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/title | "The murine ortholog of matrix metalloproteinase 19: its cloning, gene organization, and expression."xsd:string |
http://purl.uniprot.org/citations/11054540 | http://purl.uniprot.org/core/title | "The murine ortholog of matrix metalloproteinase 19: its cloning, gene organization, and expression."xsd:string |