| http://purl.uniprot.org/citations/11056535 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11056535 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11056535 | http://www.w3.org/2000/01/rdf-schema#comment | "Although cAMP is well known to regulate exocytosis in many secretory cells, its direct target in the exocytotic machinery is not known. Here we show that cAMP-GEFII, a cAMP sensor, binds to Rim (Rab3-interacting molecule, Rab3 being a small G protein) and to a new isoform, Rim2, both of which are putative regulators of fusion of vesicles to the plasma membrane. We also show that cAMP-GEFII, through its interaction with Rim2, mediates cAMP-induced, Ca2+-dependent secretion that is not blocked by an inhibitor of cAMP-dependent protein kinase (PKA). Accordingly, cAMP-GEFII is a direct target of cAMP in regulated exocytosis and is responsible for cAMP-dependent, PKA-independent exocytosis."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.org/dc/terms/identifier | "doi:10.1038/35041046"xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.org/dc/terms/identifier | "doi:10.1038/35041046"xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Matsuura Y."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Matsuura Y."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Miki T."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Miki T."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Takahashi K."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Takahashi K."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Ueno H."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Ueno H."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Ozaki N."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Ozaki N."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Seino S."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Seino S."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Iwanaga T."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Iwanaga T."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Yano H."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Yano H."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Kashima Y."xsd:string |
| http://purl.uniprot.org/citations/11056535 | http://purl.uniprot.org/core/author | "Kashima Y."xsd:string |