http://purl.uniprot.org/citations/11058122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11058122 | http://www.w3.org/2000/01/rdf-schema#comment | "Sensitivity of meiotic cells to DNA damaging agents is little understood. We have demonstrated that the meiotic pachytene nuclei in the Caenorhabditis elegans gonad are hyper-resistant to X-ray irradiation, but not to UV irradiation, whereas the early embryonic cells after fertilization and the full grown oocytes are not. The Ce-rdh-1 gene [RAD51, DMC1 (LIM15), homolog 1 or Ce-rad-51], which is essential for the meiotic recombination, is the only bacterial recA-like gene in the nematode genome, and is strongly expressed in the meiotic cells. Following silencing of the Ce-rdh-1 gene by RNA interference, the meiotic cells become more sensitive to X-ray irradiation than the early embryonic cells. This is the first report that meiotic cells are hyper-resistant to DNA strand breaks due to the high level of expression of the enzyme(s) involved in meiotic homologous recombination."xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/28.21.4232"xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/author | "Mori A."xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/author | "Takahashi H."xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/author | "Higashitani A."xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/author | "Takanami T."xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/name | "Nucleic Acids Res"xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/pages | "4232-4236"xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/title | "Hyper-resistance of meiotic cells to radiation due to a strong expression of a single recA-like gene in Caenorhabditis elegans."xsd:string |
http://purl.uniprot.org/citations/11058122 | http://purl.uniprot.org/core/volume | "28"xsd:string |
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http://purl.uniprot.org/citations/11058122 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11058122 |
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http://purl.uniprot.org/uniprot/L8E822 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11058122 |