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http://purl.uniprot.org/citations/11060231http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11060231http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11060231http://www.w3.org/2000/01/rdf-schema#comment"In C. elegans, the descendants of the 1 degrees vulval precursor cell (VPC) establish a fixed spatial pattern of two different cell fates: E-F-F-E. The two inner granddaughters attach to the somatic gonadal anchor cell (AC) and generate four vulF cells, while the two outer granddaughters produce four vulE progeny. zmp-1::GFP, a molecular marker that distinguishes these two fates, is expressed in vulE cells, but not vulF cells. We demonstrate that a short-range AC signal is required to ensure that the pattern of vulE and vulF fates is properly established. In addition, signaling between the inner and outer 1 degrees VPC descendants, as well as intrinsic polarity of the 1 degrees VPC daughters, is involved in the asymmetric divisions of the 1 degrees VPC daughters and the proper orientation of the outcome. Finally, we provide evidence that RAS signaling is used during this new AC signaling event, while the Wnt receptor LIN-17 appears to mediate signaling between the inner and outer 1 degrees VPC descendants."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.org/dc/terms/identifier"doi:10.1242/dev.127.23.5047"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.org/dc/terms/identifier"doi:10.1242/dev.127.23.5047"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/author"Wang M."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/author"Wang M."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/author"Sternberg P.W."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/author"Sternberg P.W."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/name"Development"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/name"Development"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/pages"5047-5058"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/pages"5047-5058"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/title"Patterning of the C. elegans 1 degrees vulval lineage by RAS and Wnt pathways."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/title"Patterning of the C. elegans 1 degrees vulval lineage by RAS and Wnt pathways."xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/volume"127"xsd:string
http://purl.uniprot.org/citations/11060231http://purl.uniprot.org/core/volume"127"xsd:string
http://purl.uniprot.org/citations/11060231http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11060231
http://purl.uniprot.org/citations/11060231http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11060231
http://purl.uniprot.org/citations/11060231http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11060231
http://purl.uniprot.org/citations/11060231http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11060231
http://purl.uniprot.org/uniprot/G5EGM1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11060231
http://purl.uniprot.org/uniprot/G5EGM1#attribution-5C93824B1AD8D216A9A2E114871F492Fhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/11060231