| http://purl.uniprot.org/citations/11062264 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11062264 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11062264 | http://www.w3.org/2000/01/rdf-schema#comment | "Previously, we reported that chromosomes contain a giant filamentous protein, which we identified as titin, a component of muscle sarcomeres. Here, we report the sequence of the entire titin gene in Drosophila melanogaster, D-Titin, and show that it encodes a two-megadalton protein with significant colinear homology to the NH(2)-terminal half of vertebrate titin. Mutations in D-Titin cause chromosome undercondensation, chromosome breakage, loss of diploidy, and premature sister chromatid separation. Additionally, D-Titin mutants have defects in myoblast fusion and muscle organization. The phenotypes of the D-Titin mutants suggest parallel roles for titin in both muscle and chromosome structure and elasticity, and provide new insight into chromosome structure."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.151.3.639"xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.151.3.639"xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/author | "Andrew D.J."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/author | "Andrew D.J."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/author | "Machado C."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/author | "Machado C."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/pages | "639-652"xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/pages | "639-652"xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/title | "D-Titin: a giant protein with dual roles in chromosomes and muscles."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/title | "D-Titin: a giant protein with dual roles in chromosomes and muscles."xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/volume | "151"xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://purl.uniprot.org/core/volume | "151"xsd:string |
| http://purl.uniprot.org/citations/11062264 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11062264 |
| http://purl.uniprot.org/citations/11062264 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11062264 |
| http://purl.uniprot.org/citations/11062264 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11062264 |
| http://purl.uniprot.org/citations/11062264 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11062264 |
| http://purl.uniprot.org/embl-cds/AAF44704.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11062264 |
| http://purl.uniprot.org/embl-cds/AAF62351.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11062264 |