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http://purl.uniprot.org/citations/11081631http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11081631http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11081631http://www.w3.org/2000/01/rdf-schema#comment"Replication protein A (RPA), the nuclear ssDNA-binding protein in eukaryotes, is essential to DNA replication, recombination, and repair. We have shown that a globular domain at the C terminus of subunit RPA32 contains a specific surface that interacts in a similar manner with the DNA repair enzyme UNG2 and repair factors XPA and RAD52, each of which functions in a different repair pathway. NMR structures of the RPA32 domain, free and in complex with the minimal interaction domain of UNG2, were determined, defining a common structural basis for linking RPA to the nucleotide excision, base excision, and recombinational pathways of repairing damaged DNA. Our findings support a hand-off model for the assembly and coordination of different components of the DNA repair machinery."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)00136-7"xsd:string
http://purl.uniprot.org/citations/11081631http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)00136-7"xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Bochkarev A."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Bochkarev A."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Edwards A.M."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Edwards A.M."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Gupta R."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Gupta R."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Frappier L."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Frappier L."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Bochkareva E."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Bochkareva E."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Chazin W.J."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Chazin W.J."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Mer G."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Mer G."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Ingles C.J."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/author"Ingles C.J."xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/11081631http://purl.uniprot.org/core/name"Cell"xsd:string