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http://purl.uniprot.org/citations/11087842http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11087842http://www.w3.org/2000/01/rdf-schema#comment"A family of p160 coactivators was initially identified based on ligand-dependent interactions with nuclear receptors and thought to function, in part, by recruiting CREB-binding protein/p300 to several classes of transcription factors. One of the p160 factors, p/CIP/AIB1, often amplified and overexpressed in breast cancer, also exhibits particularly strong interaction with CREB-binding protein/p300. In this manuscript, we report that p/CIP, which exhibits regulated transfer from cytoplasm to nucleus, is required for normal somatic growth from embryonic day 13.5 through maturity. Our data suggest that a short stature phenotype of p/CIP gene-deleted mice reflect both altered regulation of insulin-like growth factor-1 (IGF-1) gene expression in specific tissues and a cell-autonomous defect of response to IGF-1, including ineffective transcriptional activities by several classes of regulated transcription factors under specific conditions. The actions of p/CIP are therefore required for full expression of a subset of genes critical for regulating physiological patterns of somatic growth in mammals."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.org/dc/terms/identifier"doi:10.1073/pnas.260463097"xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Liu F."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Wang Z."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Wu W."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Pratt K."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Rosenfeld M.G."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Glass C.K."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Rose D.W."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Herman T."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Rosenfeld R."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Krones A."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Hermanson O."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Gleiberman A."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/author"Szeto D."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/name"Proc Natl Acad Sci U S A"xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/pages"13549-13554"xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/title"Regulation of somatic growth by the p160 coactivator p/CIP."xsd:string
http://purl.uniprot.org/citations/11087842http://purl.uniprot.org/core/volume"97"xsd:string
http://purl.uniprot.org/citations/11087842http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11087842
http://purl.uniprot.org/citations/11087842http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11087842
http://purl.uniprot.org/uniprot/#_A0A087WPR8-mappedCitation-11087842http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11087842
http://purl.uniprot.org/uniprot/#_D3Z7M4-mappedCitation-11087842http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11087842