| http://purl.uniprot.org/citations/11118435 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11118435 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11118435 | http://www.w3.org/2000/01/rdf-schema#comment | "We identified the rat Sam68-like mammalian protein (rSLM-2), a member of the STAR (signal transduction and activation of RNA) protein family as a novel splicing regulatory protein. Using the yeast two-hybrid system, coimmunoprecipitations, and pull-down assays, we demonstrate that rSLM-2 interacts with various proteins involved in the regulation of alternative splicing, among them the serine/arginine-rich protein SRp30c, the splicing-associated factor YT521-B and the scaffold attachment factor B. rSLM-2 can influence the splicing pattern of the CD44v5, human transformer-2beta and tau minigenes in cotransfection experiments. This effect can be reversed by rSLM-2-interacting proteins. Employing rSLM-2 deletion variants, gel mobility shift assays, and linker scan mutations of the CD44 minigene, we show that the rSLM-2-dependent inclusion of exon v5 of the CD44 pre-mRNA is dependent on a short purine-rich sequence. Because the related protein of rSLM-2, Sam68, is believed to play a role as an adapter protein during signal transduction, we postulate that rSLM-2 is a link between signal transduction pathways and pre-mRNA processing."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m006851200"xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m006851200"xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Koenig H."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Koenig H."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Andreadis A."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Andreadis A."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Stamm S."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Stamm S."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Hartmann A.M."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Hartmann A.M."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Memmott J."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Memmott J."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Olbrich M."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Olbrich M."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Stoss O."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/author | "Stoss O."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/pages | "8665-8673"xsd:string |
| http://purl.uniprot.org/citations/11118435 | http://purl.uniprot.org/core/pages | "8665-8673"xsd:string |