| http://purl.uniprot.org/citations/11129048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11129048 | http://www.w3.org/2000/01/rdf-schema#comment | "Schizosaccharomyces pombe expresses a putative transcription factor, named Prr1, which is intriguing in the sense that it contains a bacterial type of phospho-accepting receiver domain, preceded by a mammalian heat shock factor (HSF2)-like DNA-binding domain. The receiver domain is most probably involved in an as yet unidentified histidine-to-aspartate (His-to-Asp) phosphorelay pathway in S. pombe. In this study, the structure, function, and cellular localization of Prr1 were assessed in the context of oxidative stress and His-to-Asp phosphorelay. As the most intriguing result of this study, we found that Prr1 is essential not only for the expression of genes induced by oxidative stress (e.g., ctt1+ and trr1+), but also for the expression of ste11+, which in turn is responsible for the expression of a variety of genes required for sexual development. Accordingly, Prr1-deficient cells are not only hypersensitive to oxidative stress, but also severely defective in conjugation and/or spore formation. These results suggested that the transcription factor Prr1 plays a pivotal role in an as yet unknown signal transduction pathway that is implicated in sexual differentiation. These findings are discussed with special reference to the well-characterized transcription factors Pap1 and Atf1 of S. pombe."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.org/dc/terms/identifier | "doi:10.1007/s004380000305"xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/author | "Aiba H."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/author | "Kato C."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/author | "Mizuno T."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/author | "Yamada H."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/author | "Ohmiya R."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/name | "Mol Gen Genet"xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/pages | "441-451"xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/title | "The Prr1 response regulator is essential for transcription of ste11+ and for sexual development in fission yeast."xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://purl.uniprot.org/core/volume | "264"xsd:string |
| http://purl.uniprot.org/citations/11129048 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11129048 |
| http://purl.uniprot.org/citations/11129048 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11129048 |
| http://purl.uniprot.org/uniprot/O14283#attribution-5878B0BDD42F8FD7BB0E1FE43E0C72B0 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11129048 |
| http://purl.uniprot.org/uniprot/O14283#attribution-A4D45E3FE6C717925F908622E113CE83 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11129048 |
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| http://purl.uniprot.org/uniprot/#_O14283-mappedCitation-11129048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11129048 |
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| http://purl.uniprot.org/uniprot/P52890 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11129048 |