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http://purl.uniprot.org/citations/11133384http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11133384http://www.w3.org/2000/01/rdf-schema#comment"Certain HLAs may, in part, account for differences in human immunodeficiency virus type 1 (HIV-1) susceptibility by presenting conserved immunogenic epitopes for T cell recognition. The HLA supertype A2/6802 is associated with decreased susceptibility to HIV-1 among sex workers. The alleles in this supertype present the same HIV-1 peptide epitopes for T cell recognition in some cases. This study sought to determine whether the HLA A2/6802 supertype influenced HIV-1 transmission in a prospective cohort of HIV-1-infected mothers and children in Kenya. Decreased perinatal HIV-1 infection risk was strongly associated with possession of a functional cluster of related HLA alleles, called the A2/6802 supertype (odds ratio, 0.12; 95% confidence interval, 0.03-0.54; P=.006). This effect was independent of the protective effect of maternal-child HLA discordance. These data provide further evidence that HLA supertypes are associated with differential susceptibility to HIV-1 transmission."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.org/dc/terms/identifier"doi:10.1086/318092"xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Castillo J."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Plummer F.A."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"MacDonald K.S."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Bwayo J.J."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Ndinya-Achola J."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Njenga S."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Barber B.H."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Embree J.E."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Nagelkerke N.J."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Oyug J."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/author"Ramhadin S."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/name"J Infect Dis"xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/pages"503-506"xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/title"The HLA A2/6802 supertype is associated with reduced risk of perinatal human immunodeficiency virus type 1 transmission."xsd:string
http://purl.uniprot.org/citations/11133384http://purl.uniprot.org/core/volume"183"xsd:string
http://purl.uniprot.org/citations/11133384http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11133384
http://purl.uniprot.org/citations/11133384http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11133384
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-11133384http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11133384
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-11133384http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11133384
http://purl.uniprot.org/uniprot/#_A0A0G2R0N3-mappedCitation-11133384http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11133384
http://purl.uniprot.org/uniprot/#_A0A0G2R0N4-mappedCitation-11133384http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11133384