RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/11136464http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11136464http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11136464http://www.w3.org/2000/01/rdf-schema#comment"Disaccharide transporters have not previously been identified in Schizosaccharomyces pombe. This is in contrast to Saccharomyces cerevisiae in which several maltose permeases belonging to the sugar porter (SP) family have been characterized. Here we report that a novel S. pombe gene, sut1+, encodes a proton-coupled disaccharide uptake transporter in the glycoside-pentoside-hexuronide (GPH):cation symporter family. Previously, members of the GPH family were restricted to bacteria and plants. The closest homologues of sut1+ are the sucrose uptake transporters (SUTs) from higher plants that transport sucrose with a higher affinity than maltose. The transport function of Sut1p was analysed by expression in S. cerevisiae. Sut1p was found to transport maltose with a Km of 6.5 +/- 0.4 mM and sucrose with a Km of 36.3 +/-9.7 mM. Therefore, the substrate specificity of Sut1p from S. pombe is different from that of its plant homologues. Glucose repression of sut1+ at the transcriptional level is also consistent with a physiological function for Sut1p in maltose uptake. These results indicate that, unlike S. cerevisiae, S. pombe utilizes maltose transporters derived from a common ancestor with the plant SUTs."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.org/dc/terms/identifier"doi:10.1046/j.1365-2958.2001.02237.x"xsd:string
http://purl.uniprot.org/citations/11136464http://purl.org/dc/terms/identifier"doi:10.1046/j.1365-2958.2001.02237.x"xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/author"Ward J.M."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/author"Ward J.M."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/author"Reinders A."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/author"Reinders A."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/pages"445-454"xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/pages"445-454"xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/title"Functional characterization of the alpha-glucoside transporter Sut1p from Schizosaccharomyces pombe, the first fungal homologue of plant sucrose transporters."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/title"Functional characterization of the alpha-glucoside transporter Sut1p from Schizosaccharomyces pombe, the first fungal homologue of plant sucrose transporters."xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/volume"39"xsd:string
http://purl.uniprot.org/citations/11136464http://purl.uniprot.org/core/volume"39"xsd:string
http://purl.uniprot.org/citations/11136464http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11136464
http://purl.uniprot.org/citations/11136464http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11136464
http://purl.uniprot.org/citations/11136464http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11136464
http://purl.uniprot.org/citations/11136464http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11136464
http://purl.uniprot.org/uniprot/O14091http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11136464
http://purl.uniprot.org/uniprot/O14091#attribution-292C6212DA911D3EBBFF03E48CC67A94http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/11136464